MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells

Renal fibrosis is the main pathological characteristic of chronic kidney disease (CKD), whereas the underlying mechanisms of renal fibrosis are not clear yet. Herein, we found an increased expression of microRNA-34a (miR-34a) in renal tubular epithelial cells of patients with renal fibrosis and mice...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Liu, Yong, Bi, Xianjin, Xiong, Jiachuan, Han, Wenhao, Xiao, Tangli, Xu, Xinli, Yang, Ke, Liu, Chi, Jiang, Wei, He, Ting, Yu, Yanlin, Li, Yan, Zhang, Jingbo, Zhang, Bo, Zhao, Jinghong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520492/
https://ncbi.nlm.nih.gov/pubmed/30853453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.02.009
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