MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells

Renal fibrosis is the main pathological characteristic of chronic kidney disease (CKD), whereas the underlying mechanisms of renal fibrosis are not clear yet. Herein, we found an increased expression of microRNA-34a (miR-34a) in renal tubular epithelial cells of patients with renal fibrosis and mice...

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Publicat a:Mol Ther
Autors principals: Liu, Yong, Bi, Xianjin, Xiong, Jiachuan, Han, Wenhao, Xiao, Tangli, Xu, Xinli, Yang, Ke, Liu, Chi, Jiang, Wei, He, Ting, Yu, Yanlin, Li, Yan, Zhang, Jingbo, Zhang, Bo, Zhao, Jinghong
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2019
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520492/
https://ncbi.nlm.nih.gov/pubmed/30853453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.02.009
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