MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells

Renal fibrosis is the main pathological characteristic of chronic kidney disease (CKD), whereas the underlying mechanisms of renal fibrosis are not clear yet. Herein, we found an increased expression of microRNA-34a (miR-34a) in renal tubular epithelial cells of patients with renal fibrosis and mice...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Liu, Yong, Bi, Xianjin, Xiong, Jiachuan, Han, Wenhao, Xiao, Tangli, Xu, Xinli, Yang, Ke, Liu, Chi, Jiang, Wei, He, Ting, Yu, Yanlin, Li, Yan, Zhang, Jingbo, Zhang, Bo, Zhao, Jinghong
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520492/
https://ncbi.nlm.nih.gov/pubmed/30853453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.02.009
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