Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells

BACKGROUND: Klotho is a multifunctional protein, which exists both in a membrane bound and a soluble form. In renal tubules, Klotho is involved in cell senescence, anti-oxidant response, and renal fibrosis, thus regulation of its expression is critical to understand its roles in renal diseases. Inde...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Mol Cell Biol
Main Authors: Li, Yan, Liu, Yong, Wang, Kailong, Huang, Yinghui, Han, Wenhao, Xiong, Jiachuan, Yang, Ke, Liu, Mingying, Xiao, Tangli, Liu, Chi, He, Ting, Bi, Xianjin, Zhang, Jingbo, Zhang, Bo, Zhao, Jinghong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309980/
https://ncbi.nlm.nih.gov/pubmed/32571212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00292-z
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