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Therapeutic Potential of Wnt and Notch Signaling and Epigenetic Regulation in Mammalian Sensory Hair Cell Regeneration

Hearing loss is one of the most prevalent sensory deficits worldwide and can result from the death of mechanosensory hair cells that transduce auditory signals in the cochlea. The mammalian cochlea lacks the capacity to regenerate these hair cells once damaged, and currently there are no biological...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Samarajeewa, Anshula, Jacques, Bonnie E., Dabdoub, Alain
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520458/
https://ncbi.nlm.nih.gov/pubmed/30982678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.03.017
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