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Early Steps in Herpes Simplex Virus Infection Blocked by a Proteasome Inhibitor

Viruses commandeer host cell 26S proteasome activity to promote viral entry, gene expression, replication, assembly, and egress. Proteasomal degradation activity is critical for herpes simplex virus (HSV) infection. The proteasome inhibitor bortezomib (also known as Velcade and PS-341) is a clinical...

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Bibliografische gegevens
Gepubliceerd in:mBio
Hoofdauteurs: Schneider, Seth M., Pritchard, Suzanne M., Wudiri, George A., Trammell, Chasity E., Nicola, Anthony V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520451/
https://ncbi.nlm.nih.gov/pubmed/31088925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00732-19
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