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Early Steps in Herpes Simplex Virus Infection Blocked by a Proteasome Inhibitor

Viruses commandeer host cell 26S proteasome activity to promote viral entry, gene expression, replication, assembly, and egress. Proteasomal degradation activity is critical for herpes simplex virus (HSV) infection. The proteasome inhibitor bortezomib (also known as Velcade and PS-341) is a clinical...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:mBio
Main Authors: Schneider, Seth M., Pritchard, Suzanne M., Wudiri, George A., Trammell, Chasity E., Nicola, Anthony V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520451/
https://ncbi.nlm.nih.gov/pubmed/31088925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00732-19
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