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Cellular Cholesterol Facilitates the Postentry Replication Cycle of Herpes Simplex Virus 1

Cholesterol is an essential component of cell membranes and is required for herpes simplex virus 1 (HSV-1) entry (1–3). Treatment of HSV-1-infected Vero cells with methyl beta-cyclodextrin from 2 to 9 h postentry reduced plaque numbers. Transport of incoming viral capsids to the nuclear periphery wa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wudiri, George A., Nicola, Anthony V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487575/
https://ncbi.nlm.nih.gov/pubmed/28446672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00445-17
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