Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Through combined genetic, in silico, in vitro, and ex vivo approaches, we define CXorf21, a gene of hitherto unk...

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Udgivet i:Nat Commun
Main Authors: Odhams, Christopher A., Roberts, Amy L., Vester, Susan K., Duarte, Carolina S. T., Beales, Charlie T., Clarke, Alexander J., Lindinger, Sonja, Daffern, Samuel J., Zito, Antonino, Chen, Lingyan, Jones, Leonardo L., Boteva, Lora, Morris, David L., Small, Kerrin S., Fernando, Michelle M. A., Cunninghame Graham, Deborah S., Vyse, Timothy J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520347/
https://ncbi.nlm.nih.gov/pubmed/31092820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10106-2
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