Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity

Using three European and two Chinese genome-wide association studies (GWAS), we investigated the performance of genetic risk scores (GRSs) for predicting the susceptibility and severity of systemic lupus erythematosus (SLE), using renal disease as a proxy for severity. We used four GWASs to test the...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Chen, Lingyan, Wang, Yong-Fei, Liu, Lu, Bielowka, Adrianna, Ahmed, Rahell, Zhang, Huoru, Tombleson, Phil, Roberts, Amy L, Odhams, Christopher A, Cunninghame Graham, Deborah S, Zhang, Xuejun, Yang, Wanling, Vyse, Timothy J, Morris, David L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322569/
https://ncbi.nlm.nih.gov/pubmed/32077931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa030
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