Independent Replication on Genome-Wide Association Study Signals Identifies IRF3 as a Novel Locus for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease. Despite the significant progress made in identifying susceptibility genes for SLE, the genetic architecture of the disease is far from being understood. In this study, we set to replicate a number of suggestive associati...

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Vydáno v:Front Genet
Hlavní autoři: Zhang, Feixia, Wang, Yong-Fei, Zhang, Yan, Lin, Zhiming, Cao, Yujie, Zhang, Huoru, Liu, Zhong-Yi, Morris, David L., Sheng, Yujun, Cui, Yong, Zhang, Xuejun, Vyse, Timothy J., Lau, Yu Lung, Yang, Wanling, Chen, Yanhui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348047/
https://ncbi.nlm.nih.gov/pubmed/32719713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00600
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