Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes

Polycomb repressive complexes are evolutionarily conserved complexes that maintain transcriptional repression during development and differentiation to establish and preserve cell identity. We recently described the fundamental role of PRC1 in preserving intestinal stem cell identity through the inh...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Adv
Auteurs principaux: Pivetti, Silvia, Fernandez-Perez, Daniel, D’Ambrosio, Alessandro, Barbieri, Caterina Maria, Manganaro, Daria, Rossi, Alessandra, Barnabei, Laura, Zanotti, Marika, Scelfo, Andrea, Chiacchiera, Fulvio, Pasini, Diego
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2019
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520019/
https://ncbi.nlm.nih.gov/pubmed/31106267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav1594
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