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Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes

Polycomb repressive complexes are evolutionarily conserved complexes that maintain transcriptional repression during development and differentiation to establish and preserve cell identity. We recently described the fundamental role of PRC1 in preserving intestinal stem cell identity through the inh...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Pivetti, Silvia, Fernandez-Perez, Daniel, D’Ambrosio, Alessandro, Barbieri, Caterina Maria, Manganaro, Daria, Rossi, Alessandra, Barnabei, Laura, Zanotti, Marika, Scelfo, Andrea, Chiacchiera, Fulvio, Pasini, Diego
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520019/
https://ncbi.nlm.nih.gov/pubmed/31106267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav1594
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