Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes

Polycomb repressive complexes are evolutionarily conserved complexes that maintain transcriptional repression during development and differentiation to establish and preserve cell identity. We recently described the fundamental role of PRC1 in preserving intestinal stem cell identity through the inh...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Pivetti, Silvia, Fernandez-Perez, Daniel, D’Ambrosio, Alessandro, Barbieri, Caterina Maria, Manganaro, Daria, Rossi, Alessandra, Barnabei, Laura, Zanotti, Marika, Scelfo, Andrea, Chiacchiera, Fulvio, Pasini, Diego
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520019/
https://ncbi.nlm.nih.gov/pubmed/31106267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav1594
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