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Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes
Polycomb repressive complexes are evolutionarily conserved complexes that maintain transcriptional repression during development and differentiation to establish and preserve cell identity. We recently described the fundamental role of PRC1 in preserving intestinal stem cell identity through the inh...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6520019/ https://ncbi.nlm.nih.gov/pubmed/31106267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav1594 |
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