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Thrombin-cleaved syndecan-3/-4 ectodomain fragments mediate endothelial barrier dysfunction

OBJECTIVE: The endothelial glycocalyx constitutes part of the endothelial barrier but its degradation leaves endothelial cells exposed to transmigrating cells and circulating mediators that can damage the barrier or promote intercellular gaps. Syndecan proteins are key components of the endothelial...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jannaway, Melanie, Yang, Xiaoyuan, Meegan, Jamie E., Coleman, Danielle C., Yuan, Sarah Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519803/
https://ncbi.nlm.nih.gov/pubmed/31091226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214737
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