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Endothelial dysfunction is a superinducer of syndecan-4: fibrogenic role of its ectodomain

Syndecan-4 (Synd4) is a member of the membrane-spanning, glycocalyx-forming proteoglycan family. It has been suggested that Synd4 participates in renal fibrosis. We compared wild-type and fibrosis-prone endothelial sirtuin 1-deficient (Sirt1(endo−/−)) mice, the latter being a model of global endothe...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Lipphardt, Mark, Song, Jong W., Ratliff, Brian B., Dihazi, Hassan, Müller, Gerhard A., Goligorsky, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899265/
https://ncbi.nlm.nih.gov/pubmed/29101181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00548.2017
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