A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation

AIMS: Endothelial hyperpermeability exacerbates multiple organ damage during inflammation or infection. The endothelial glycocalyx, a protective matrix covering the luminal surface of endothelial cells (ECs), undergoes enzymatic shedding during inflammation, contributing to barrier hyperpermeability...

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Bibliographic Details
Published in:Cardiovasc Res
Main Authors: Yang, Xiaoyuan, Meegan, Jamie E, Jannaway, Melanie, Coleman, Danielle C, Yuan, Sarah Y
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198742/
https://ncbi.nlm.nih.gov/pubmed/29939250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy167
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