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Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG

The major facilitator superfamily transporter Rv1410 and the lipoprotein LprG (Rv1411) are encoded by a conserved two‐gene operon and contribute to virulence in Mycobacterium tuberculosis. Rv1410 was originally postulated to function as a drug efflux pump, but recent studies suggested that Rv1410 an...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Hohl, Michael, Remm, Sille, Eskandarian, Haig A., Dal Molin, Michael, Arnold, Fabian M., Hürlimann, Lea M., Krügel, Andri, Fantner, Georg E., Sander, Peter, Seeger, Markus A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519032/
https://ncbi.nlm.nih.gov/pubmed/30742339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14220
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