High glucose promotes pancreatic cancer cells to escape from immune surveillance via AMPK-Bmi1-GATA2-MICA/B pathway

BACKGROUND: Modulation of cell surface expression of MHC class I chain-related protein A/B (MICA/B) has been proven to be one of the mechanisms by which tumor cells escape from NK cell-mediated killing. Abnormal metabolic condition, such as high glucose, may create a cellular stress milieu to induce...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Duan, Qingke, Li, Hehe, Gao, Chenggang, Zhao, Hengqiang, Wu, Shihong, Wu, Heshui, Wang, Chunyou, Shen, Qiang, Yin, Tao
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518784/
https://ncbi.nlm.nih.gov/pubmed/31088566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1209-9
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares