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Up‐regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine‐resistant pancreatic cancer cells

Cancer stem cells (CSCs) and epithelial–mesenchymal transition (EMT)‐type cells are considered as underlying causes of chemoresistance, tumour recurrence and metastasis in pancreatic cancer. We aimed to describe the mechanisms – particularly glycolysis – involved in the regulation of the CSC and EMT...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Principais autores: Zhao, Hengqiang, Duan, Qingke, Zhang, Zhengle, Li, Hehe, Wu, Heshui, Shen, Qiang, Wang, Chunyou, Yin, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571518/
https://ncbi.nlm.nih.gov/pubmed/28244691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13126
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