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Up‐regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine‐resistant pancreatic cancer cells

Cancer stem cells (CSCs) and epithelial–mesenchymal transition (EMT)‐type cells are considered as underlying causes of chemoresistance, tumour recurrence and metastasis in pancreatic cancer. We aimed to describe the mechanisms – particularly glycolysis – involved in the regulation of the CSC and EMT...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Zhao, Hengqiang, Duan, Qingke, Zhang, Zhengle, Li, Hehe, Wu, Heshui, Shen, Qiang, Wang, Chunyou, Yin, Tao
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571518/
https://ncbi.nlm.nih.gov/pubmed/28244691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13126
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