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Up‐regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine‐resistant pancreatic cancer cells

Cancer stem cells (CSCs) and epithelial–mesenchymal transition (EMT)‐type cells are considered as underlying causes of chemoresistance, tumour recurrence and metastasis in pancreatic cancer. We aimed to describe the mechanisms – particularly glycolysis – involved in the regulation of the CSC and EMT...

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Bibliografski detalji
Izdano u:J Cell Mol Med
Glavni autori: Zhao, Hengqiang, Duan, Qingke, Zhang, Zhengle, Li, Hehe, Wu, Heshui, Shen, Qiang, Wang, Chunyou, Yin, Tao
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571518/
https://ncbi.nlm.nih.gov/pubmed/28244691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13126
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