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The CD44s splice isoform is a central mediator for invadopodia activity
The ability for tumor cells to spread and metastasize to distant organs requires proteolytic degradation of extracellular matrix (ECM). This activity is mediated by invadopodia, actin-rich membrane protrusions that are enriched for proteases. However, the mechanisms underlying invadopodia activity a...
Shranjeno v:
| izdano v: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Company of Biologists Ltd
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6518308/ https://ncbi.nlm.nih.gov/pubmed/26869223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.171959 |
| Oznake: |
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