Dysregulated megakaryocyte distribution associated with nestin(+) mesenchymal stem cells in immune thrombocytopenia

Impaired megakaryocyte (MK) maturation and reduced platelet production are important causes of immune thrombocytopenia (ITP). However, MK distribution and bone marrow (BM) niche alteration in ITP are unclear. To investigate the maturation and distribution of MKs in the BM niche and examine the compo...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Wang, Min, Feng, Ru, Zhang, Jia-min, Xu, Lin-lin, Feng, Fei-er, Wang, Chen-cong, Wang, Qian-ming, Zhu, Xiao-lu, He, Yun, Xue, Jing, Fu, Hai-xia, Lv, Meng, Kong, Yuan, Chang, Ying-jun, Xu, Lan-ping, Liu, Kai-yan, Huang, Xiao-jun, Zhang, Xiao-hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2019
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517671/
https://ncbi.nlm.nih.gov/pubmed/31053569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026690
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