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Phthalides serve as potent modulators to boost fetal hemoglobin induction therapy for β-hemoglobinopathies
Fetal hemoglobin (HbF) induction therapy has become the most promising strategy for treating β-hemoglobinopathies, including sickle-cell diseases and β-thalassemia. However, subtle but critical structural difference exists between HbF and normal adult hemoglobin (HbA), which inevitably leads to redu...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517670/ https://ncbi.nlm.nih.gov/pubmed/31072835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019031120 |
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