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The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells

Hu antigen R (HuR) is indeed one of the most studied RNA-binding protein (RBP) since its fundamental role both in tumorigenesis and cancer progression. For this reason, downregulation in HuR protein levels or inhibition of HuR biological function are, nowadays, attractive goals in cancer research. H...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Allegri, Lorenzo, Baldan, Federica, Roy, Sudeshna, Aubé, Jeffrey, Russo, Diego, Filetti, Sebastiano, Damante, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517587/
https://ncbi.nlm.nih.gov/pubmed/31089242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43894-0
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