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The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells

Hu antigen R (HuR) is indeed one of the most studied RNA-binding protein (RBP) since its fundamental role both in tumorigenesis and cancer progression. For this reason, downregulation in HuR protein levels or inhibition of HuR biological function are, nowadays, attractive goals in cancer research. H...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Allegri, Lorenzo, Baldan, Federica, Roy, Sudeshna, Aubé, Jeffrey, Russo, Diego, Filetti, Sebastiano, Damante, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517587/
https://ncbi.nlm.nih.gov/pubmed/31089242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43894-0
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