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Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action

Exposure to toxic levels of hydrogen sulfide (H(2)S) produces an acute cardiac depression that can be rapidly fatal. We sought to characterize the time course of the cardiac effects produced by the toxicity of H(2)S in sheep, a human sized mammal, and to describe the in vivo and in vitro antidotal p...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Haouzi, Philippe, Tubbs, Nicole, Cheung, Joseph, Judenherc-Haouzi, Annick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516679/
https://ncbi.nlm.nih.gov/pubmed/30590764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy308
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