Antidotal effects of methylene blue against cyanide neurological toxicity: in vivo and in vitro studies

The aim of the present study was to determine whether methylene blue (MB) could directly oppose the neurological toxicity of a lethal cyanide (CN) intoxication. KCN, infused at the rate of 0.375 mg/kg/min intravenously, produced 100% lethality within 15 min in unanaesthetized rats (n = 12). MB at 10...

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Vydáno v:Ann N Y Acad Sci
Hlavní autoři: Haouzi, Philippe, McCann, Marissa, Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Sariyer, Ilker, Langford, Diane, Santerre, Maryline, Tubbs, Nicole, Haouzi-Judenherc, Annick, Cheung, Joseph Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644644/
https://ncbi.nlm.nih.gov/pubmed/32374444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14353
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