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Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action

Exposure to toxic levels of hydrogen sulfide (H(2)S) produces an acute cardiac depression that can be rapidly fatal. We sought to characterize the time course of the cardiac effects produced by the toxicity of H(2)S in sheep, a human sized mammal, and to describe the in vivo and in vitro antidotal p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Toxicol Sci
Main Authors: Haouzi, Philippe, Tubbs, Nicole, Cheung, Joseph, Judenherc-Haouzi, Annick
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516679/
https://ncbi.nlm.nih.gov/pubmed/30590764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy308
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