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Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action

Exposure to toxic levels of hydrogen sulfide (H(2)S) produces an acute cardiac depression that can be rapidly fatal. We sought to characterize the time course of the cardiac effects produced by the toxicity of H(2)S in sheep, a human sized mammal, and to describe the in vivo and in vitro antidotal p...

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Vydáno v:Toxicol Sci
Hlavní autoři: Haouzi, Philippe, Tubbs, Nicole, Cheung, Joseph, Judenherc-Haouzi, Annick
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516679/
https://ncbi.nlm.nih.gov/pubmed/30590764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy308
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