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The leptin sensitizer celastrol reduces age‐associated obesity and modulates behavioral rhythms
The prevalence of obesity increases with age in humans and in rodents. Age‐related obesity is characterized by leptin resistance and associated with heightened risk of metabolic disorders. However, the effect of leptin resistance per se has been difficult to disentangle from other effects of aging....
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| Publicado no: | Aging Cell |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516176/ https://ncbi.nlm.nih.gov/pubmed/30821426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12874 |
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