1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling

We tested the hypothesis that 1,25‐dihydroxyvitamin D(3)[1α,25(OH)(2)D(3)] has antiaging effects via upregulating nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2), reducing reactive oxygen species (ROS), decreasing DNA damage, reducing p16/Rb and p53/p21 signaling, increasing cell proliferation, a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Chen, Lulu, Yang, Renlei, Qiao, Wanxin, Zhang, Wei, Chen, Jie, Mao, Li, Goltzman, David, Miao, Dengshun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516172/
https://ncbi.nlm.nih.gov/pubmed/30907059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12951
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