SIRT1/FOXO3a axis plays an important role in the prevention of mandibular bone loss induced by 1,25(OH)(2)D deficiency

It has been reported that 1,25 dihydroxyvitamin D [1,25(OH)(2)D] deficiency leads to the loss of mandibular bone, however the mechanism is unclear. We investigated whether the Sirt1/FOXO3a signaling pathway is involved in this process. Using a 1,25(OH)(2)D deficiency model induced by genetic deletio...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Chen, Haiyun, Hu, Xiaoqing, Yang, Renlei, Wu, Guoping, Tan, Qian, Goltzman, David, Miao, Dengshun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586429/
https://ncbi.nlm.nih.gov/pubmed/33110391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.48169
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