ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice

BACKGROUND: Alzheimer’s disease (AD) is defined by amyloid beta (Aβ) plaques and neurofibrillary tangles and characterized by neurodegeneration and memory loss. The majority of AD patients also have Aβ deposition in cerebral vessels known as cerebral amyloid angiopathy (CAA), microhemorrhages, and v...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Res Ther
Hauptverfasser: Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie, Hayat, Arooj, Fan, Jianjia, Wadsworth, Brennan J., Robert, Jerome, Martens, Kris M., Wellington, Cheryl L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515644/
https://ncbi.nlm.nih.gov/pubmed/31084613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0497-9
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge