Intermittent Hypoxia Up-Regulates CCL2, RETN, and TNFα mRNAs in Adipocytes via Down-regulation of miR-452

Sleep apnea syndrome (SAS), characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia [IH]), is a risk factor for insulin resistance. Recently, IH is considered to independently cause adipose tissue inflammation/dysfunction, leading to worsening insulin resis...

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Udgivet i:Int J Mol Sci
Main Authors: Uchiyama, Tomoko, Itaya-Hironaka, Asako, Yamauchi, Akiyo, Makino, Mai, Sakuramoto-Tsuchida, Sumiyo, Shobatake, Ryogo, Ota, Hiroyo, Takeda, Maiko, Ohbayashi, Chiho, Takasawa, Shin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515141/
https://ncbi.nlm.nih.gov/pubmed/31013606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081960
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