Up-regulation of selenoprotein P and HIP/PAP mRNAs in hepatocytes by intermittent hypoxia via down-regulation of miR-203

Sleep apnea syndrome is characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia [IH]) and is a risk factor for insulin resistance/type 2 diabetes. However, the mechanisms linking IH stress and insulin resistance remain elusive. We exposed human hepatocytes...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Uchiyama, Tomoko, Ota, Hiroyo, Itaya-Hironaka, Asako, Shobatake, Ryogo, Yamauchi, Akiyo, Sakuramoto-Tsuchida, Sumiyo, Makino, Mai, Kimura, Hiroshi, Takeda, Maiko, Ohbayashi, Chiho, Takasawa, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614699/
https://ncbi.nlm.nih.gov/pubmed/28955777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.07.005
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