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Spiro Indane-Based Phosphine-Oxazolines as Highly Efficient P,N Ligands for Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles and Allylic Etherification

A series of indane-based phosphine-oxazoline ligands with a spirocarbon stereogenic center were examined for palladium-catalyzed asymmetric allylic alkylation of indoles. Under optimized conditions, high yields (up to 98%) and enantioselectivities (up to 98% ee) were obtained with a broad scope of i...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Qiu, Zhongxuan, Sun, Rui, Yang, Kun, Teng, Dawei
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515030/
https://ncbi.nlm.nih.gov/pubmed/31010104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24081575
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