Amyloid-β oligomers have a profound detergent-like effect on lipid membrane bilayers, imaged by atomic force and electron microscopy

The ability of amyloid-β peptide (Aβ) to disrupt membrane integrity and cellular homeostasis is believed to be central to Alzheimer's disease pathology. Aβ is reported to have various impacts on the lipid bilayer, but a clearer picture of Aβ influence on membranes is required. Here, we use atom...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Bode, David C., Freeley, Mark, Nield, Jon, Palma, Matteo, Viles, John H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Accelerated Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514634/
https://ncbi.nlm.nih.gov/pubmed/30948512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.007195
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