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Proteolytic dynamics of human 20S thymoproteasome

An efficient immunosurveillance of CD8(+) T cells in the periphery depends on positive/negative selection of thymocytes and thus on the dynamics of antigen degradation and epitope production by thymoproteasome and immunoproteasome in the thymus. Although studies in mouse systems have shown how thymo...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Kuckelkorn, Ulrike, Stübler, Sabine, Textoris-Taube, Kathrin, Kilian, Christiane, Niewienda, Agathe, Henklein, Petra, Janek, Katharina, Stumpf, Michael P. H., Mishto, Michele, Liepe, Juliane
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514615/
https://ncbi.nlm.nih.gov/pubmed/30914481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007347
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