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Proteolytic dynamics of human 20S thymoproteasome

An efficient immunosurveillance of CD8(+) T cells in the periphery depends on positive/negative selection of thymocytes and thus on the dynamics of antigen degradation and epitope production by thymoproteasome and immunoproteasome in the thymus. Although studies in mouse systems have shown how thymo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kuckelkorn, Ulrike, Stübler, Sabine, Textoris-Taube, Kathrin, Kilian, Christiane, Niewienda, Agathe, Henklein, Petra, Janek, Katharina, Stumpf, Michael P. H., Mishto, Michele, Liepe, Juliane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514615/
https://ncbi.nlm.nih.gov/pubmed/30914481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007347
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