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The Origin and Evolution of Release Factors: Implications for Translation Termination, Ribosome Rescue, and Quality Control Pathways

The evolution of release factors catalyzing the hydrolysis of the final peptidyl-tRNA bond and the release of the polypeptide from the ribosome has been a longstanding paradox. While the components of the translation apparatus are generally well-conserved across extant life, structurally unrelated r...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Burroughs, A. Maxwell, Aravind, L
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514570/
https://ncbi.nlm.nih.gov/pubmed/31018531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081981
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