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Distinct types of translation termination generate substrates for ribosome-associated quality control

Cotranslational degradation of polypeptide nascent chains plays a critical role in quality control of protein synthesis and the rescue of stalled ribosomes. In eukaryotes, ribosome stalling triggers release of 60S subunits with attached nascent polypeptides, which undergo ubiquitination by the E3 li...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shcherbik, Natalia, Chernova, Tatiana A., Chernoff, Yury O., Pestov, Dimitri G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001609/
https://ncbi.nlm.nih.gov/pubmed/27325745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw566
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