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Distinct types of translation termination generate substrates for ribosome-associated quality control
Cotranslational degradation of polypeptide nascent chains plays a critical role in quality control of protein synthesis and the rescue of stalled ribosomes. In eukaryotes, ribosome stalling triggers release of 60S subunits with attached nascent polypeptides, which undergo ubiquitination by the E3 li...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001609/ https://ncbi.nlm.nih.gov/pubmed/27325745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw566 |
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