Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos

How divergent genetic systems regulate a common pathway during the development of two serial structures, forelimbs and hindlimbs, is not well understood. Specifically, HAND2 has been shown to regulate Shh directly to initiate its expression in the posterior margin of the limb mesenchyme. Although th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Development
Auteurs principaux: Itou, Junji, Kawakami, Hiroko, Quach, Thu, Osterwalder, Marco, Evans, Sylvia M., Zeller, Rolf, Kawakami, Yasuhiko
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2012
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514305/
https://ncbi.nlm.nih.gov/pubmed/22438573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.073056
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