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HMGB factors are required for posterior digit development through integrating signaling pathway activities

The chromatin factors Hmgb1 and Hmgb2 have critical roles in cellular processes, including transcription and DNA modification. To identify the function of Hmgb genes in embryonic development, we generated double mutants of Hmgb1;Hmgb2 in mice. While double null embryos arrest at E9.5, Hmgb1(-/-);Hmg...

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Detalhes bibliográficos
Main Authors: Itou, Junji, Taniguchi, Noboru, Oishi, Isao, Kawakami, Hiroko, Lotz, Martin, Kawakami, Yasuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081368/
https://ncbi.nlm.nih.gov/pubmed/21384471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22598
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