The δ‐opioid receptor positive allosteric modulator BMS 986187 is a G‐protein‐biased allosteric agonist

BACKGROUND AND PURPOSE: The δ‐opioid receptor is an emerging target for the management of chronic pain and depression. Biased signalling, the preferential activation of one signalling pathway over another downstream of δ‐receptors, may generate better therapeutic profiles. BMS 986187 is a positive a...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Stanczyk, M. Alexander, Livingston, Kathryn E., Chang, Louise, Weinberg, Zara Y., Puthenveedu, Manojkumar A., Traynor, John R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514288/
https://ncbi.nlm.nih.gov/pubmed/30710458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14602
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