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Renal Clearance in Newborns and Infants: Predictive Performance of Population- Based Modeling for Drug Development

The objective of this study was to evaluate the predictive performance of population models to predict renal clearance in newborns and infants. Pharmacokinetic (PK) data from eight drugs in 788 newborns and infants were used to evaluate the predictive performance of the population models based on po...

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Dettagli Bibliografici
Pubblicato in:Clin Pharmacol Ther
Autori principali: Wang, Jian, Kumar, Shaun S., Sherwin, Catherine M., Ward, Robert, Baer, Gerri, Burckart, Gilbert J., Wang, Yaning, Yao, Lynne P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513721/
https://ncbi.nlm.nih.gov/pubmed/30565653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1332
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