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Renal Clearance in Newborns and Infants: Predictive Performance of Population- Based Modeling for Drug Development

The objective of this study was to evaluate the predictive performance of population models to predict renal clearance in newborns and infants. Pharmacokinetic (PK) data from eight drugs in 788 newborns and infants were used to evaluate the predictive performance of the population models based on po...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Wang, Jian, Kumar, Shaun S., Sherwin, Catherine M., Ward, Robert, Baer, Gerri, Burckart, Gilbert J., Wang, Yaning, Yao, Lynne P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513721/
https://ncbi.nlm.nih.gov/pubmed/30565653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1332
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