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Genetic Variants Associated with Vincristine-Induced Peripheral Neuropathy in Two Populations of Children with Acute Lymphoblastic Leukemia

Vincristine is one of the core chemotherapy agents used in the treatment of pediatric acute lymphoblastic leukemia (ALL). However, one of the major toxicities resulting from vincristine exposure is vincristine-induced peripheral neuropathy (VIPN). When VIPN results in significant morbidity, the vinc...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Pharmacol Ther
Hauptverfasser: Li, Lang, Sajdyk, Tammy, Smith, Ellen M. L., Chang, Chien Wei, Li, Claire, Ho, Richard H., Hutchinson, Raymond, Wells, Elizabeth, Skiles, Jodi L., Winick, Naomi, Renbarger, Jamie L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513686/
https://ncbi.nlm.nih.gov/pubmed/30506673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1324
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