Genetic Variants Associated with Vincristine-Induced Peripheral Neuropathy in Two Populations of Children with Acute Lymphoblastic Leukemia

Vincristine is one of the core chemotherapy agents used in the treatment of pediatric acute lymphoblastic leukemia (ALL). However, one of the major toxicities resulting from vincristine exposure is vincristine-induced peripheral neuropathy (VIPN). When VIPN results in significant morbidity, the vinc...

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Détails bibliographiques
Publié dans:Clin Pharmacol Ther
Auteurs principaux: Li, Lang, Sajdyk, Tammy, Smith, Ellen M. L., Chang, Chien Wei, Li, Claire, Ho, Richard H., Hutchinson, Raymond, Wells, Elizabeth, Skiles, Jodi L., Winick, Naomi, Renbarger, Jamie L.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513686/
https://ncbi.nlm.nih.gov/pubmed/30506673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1324
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