A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral Neuropathy

Vincristine is a core chemotherapeutic drug administered to pediatric acute lymphoblastic leukemia patients. Despite its efficacy in treating leukemia, it can lead to severe peripheral neuropathy in a subgroup of the patients. Peripheral neuropathy is a debilitating and painful side-effect that can...

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Udgivet i:Sci Rep
Main Authors: Verma, Parul, Devaraj, Jayachandran, Skiles, Jodi L., Sajdyk, Tammy, Ho, Richard H., Hutchinson, Raymond, Wells, Elizabeth, Li, Lang, Renbarger, Jamie, Cooper, Bruce, Ramkrishna, Doraiswami
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295796/
https://ncbi.nlm.nih.gov/pubmed/32541868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66815-y
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