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HIV blocks Type I IFN signaling through disruption of STAT1 phosphorylation
This study investigates the modulation of Type I IFN induction of an antiviral state by HIV. IFNs, including IFN-α, are key innate immune cytokines that activate the JAK/STAT pathway leading to the expression of IFN-stimulated genes. IFN-stimulated gene expression establishes the antiviral state, li...
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| Publicado no: | Innate Immun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6513668/ https://ncbi.nlm.nih.gov/pubmed/30282499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425918803674 |
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