Chargement en cours...
UBQLN4 promotes non-homologous end joining by repressing DNA end-resection
Ataxia-telangiectasia-mutated (ATM) promotes homologous recombination (HR)-mediated DNA double-strand break repair. It was recently shown that the proteasomal shuttle factor UBQLN4 facilitates MRE11 degradation to repress HR. Surprisingly, the UBQLN4-MRE11 interaction is ATM-dependent, suggesting th...
Enregistré dans:
| Publié dans: | Mol Cell Oncol |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512934/ https://ncbi.nlm.nih.gov/pubmed/31131301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1575692 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|