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Bismaleimide cross‐linked anthrax toxin forms functional octamers with high specificity in tumor targeting
In recent years, anthrax toxin has been reengineered to act as a highly specific antiangiogenic cancer therapeutic, shown to kill tumors in animal models. This has been achieved by modifying protective antigen (PA) so that its activation and toxicity require the presence of two proteases, matrix met...
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| Publicado no: | Protein Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511737/ https://ncbi.nlm.nih.gov/pubmed/30942916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3613 |
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